One of the central components in the antioxidant cycle is vitamin E, a potent biological antioxidant that works to stabilize highly reactive free radicals in lipid (fatty) tissues and membranes (lipoproteins). 5. Alpha-lipoic acid is a natural compound with antioxidant properties and other potential health benefits. As long as you're healthy, the body can produce all the ALA it needs for these purposes. It’s not hard to come by foods containing linoleic acid, since most processed and packaged foods are prepared with vegetable oils containing the polyunsaturated fat. (13). Alpha-linolenic acid is an essential omega-3 fatty acid. Talk to a Dr. Berg Keto Consultant today and get the help you need on your journey. 3. Learn about 10 amazing benefits of Alpha Lipoic Acid for good health. It may also be useful in preventing diabetic nerve damage and neuropathy. He is the author of best-selling book, The Alpha Lipoic Acid Breakthrough.Discover the amazing health benefits of alpha lipoic acid for your liver, diabetes, and more. What most impressed researchers was the discovery that ALA functions as both a fat and water-soluble antioxidant that can easily cross cell membranes. At IMC, Burton Berkson, M.D., Ph.D., and Arthur Berkson, MD, use both conventional and alternative therapies to treat the whole person – body, mind, and spirit. Dr. Lester Packer, senior scientist at Lawrence Berkeley Laboratory and head of the Packer Lab at th… -nutritionreview.org […], […] (01,02) NutritionReview.com(R)-Lipoic Acid. In addition to being an important free-radical deactivator, glutathione also plays a vital role in protecting against cataract formation, enhancing immune function, preventing liver damage, slowing the initiation of cancers and eliminating heavy metals. (7), Studies also indicate that mood disorders are correlated with very low concentrations of linoleic acid. Alpha-lipoic acid is a natural compound with antioxidant properties and other potential health benefits. In time researchers had access to pure samples of the natural, biological version, (R)-ALA. When you eat an excessive amount of omega-6 foods, like products made from vegetable oils, it has a pro-inflammatory response. Being uniquely fat and water-soluble permits this antioxidant fatty acid to work in a broader range of body tissues than other antioxidants, like fat-soluble vitamin E or water-soluble vitamin C. [ 4 , 5 ] . Men. Data not available. This interaction applies only to orally administered alpha-lipoic acid and orally administered iron salts. Have you heard about ALA? Today we are exposed to more toxins than our ancestors ever were. They discovered that in addition to being a powerful antioxidant in its own right, ALA is able to raise intracellular glutathione levels. Benefits of Alpha-lipoic acid One of the most attractive benefits potentially associated with Alpha Lipoic Acid is to help slow the aging proc… (3). “The therapeutic potential of alpha-lipoic acid is just beginning to be explored,’ observed Packer, ‘but this compound holds great promise.”. Is linoleic acid bad for you? Hegazy SK, Tolba OA, Mostafa TM, Eid MA, El-Afify DR. Alpha-lipoic acid improves subclinical left ventricular dysfunction in asymptomatic patients with type 1 … R-lipoic acid is directly involved in cellular metabolism and is a vital component of the intracellular antioxidant cycle, able to scavenge a variety of free radicals and reactive oxygen species (ROS) while recycling vitamins C, E and glutathione. Alpha-linolenic acid (ALA) is an essential omega-3 fatty acid. R-lipoic acid is the biologically active form of the key ‘mitochondrial antioxidant,’ alpha lipoic acid. What is a good source of linoleic acid? Animal studies indicate that this acid may be involved in neurotransmission and participates in the response to ischemic brain injury, such as stroke. Alpha lipoic acid reduced blood pressure in a study involving 70 women with rheumatoid arthritis. © Nutrition Review - All Rights Reserved, (R)-Lipoic Acid: Unique ‘Mitochondrial Antioxidant’ Fights Premature Aging. Being uniquely fat and water-soluble permits this antioxidant fatty acid to work in a broader range of body tissues than other antioxidants, like fat-soluble vitamin E or water-soluble vitamin C. [ 4 , 5 ] . Alpha lipoic acid consists of a mixture between R and S. ... and as such the benefits of lipoic acid are in this component. In 2009, the American Heart Association published an advisory recommending that at least 5 percent to 10 percent of energy from omega-6 fatty acids, primarily linoleic acid, reduces the risk of cardiovascular disease, concluding that reducing intake levels would likely increase the risk. Detox Your Liver: Try My 6-Step Liver Cleanse, Apple Cider Vinegar Benefits and Uses (30! "Alpha-lipoic acid is a strong antioxidant, and the bulk of its benefits arise from that fact." L. Packer, E.H.Witt, H.J. For example, researchers in Germany reported that, unlike the natural form, (S)-ALA does not improve ATP synthesis in isolated cells. According to Dr. Packer, ALA is more potent than vitamins C and E, and CoQ10, and may, in fact, be the most important antioxidant ever discovered. Microbes in the gastrointestinal tract of ruminants (like grass-fed beef and lamb) convert linoleic acid into CLA through a process called biohydrogenation. 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